Identification of circulatory biomarkers from clinical trial samples
نویسندگان
چکیده
Background Despite significant advances in genomics, proteomics and metabolomics, the identification and validation of circulatory immunological biomarkers in cancer patients, which could be useful to monitor disease progression and response to immunotherapeutic treatments, remains as elusive as ever. Circulatory biomarkers, being easily accessible, may provide crucial guidance and be incorporated in routine point of care practices. Immunological biomarkers could aid clinical decision making regarding initiation, cessation, boost or change of treatment and assessment of therapeutic responses. In light of the increasing number of immunotherapeutic options, this is an area receiving renewed attention.
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